39640-15-8
39640-15-8
Chemical Structure
Piberaline
Synonym(s): EGYT-475; Trelibet
- CAS No.: 39640-15-8
- Formula:C17H19N3O
- Molecular Weight:281.36
IUPAC Name: (4-benzylpiperazin-1-yl)(pyridin-2-yl)methanone
InChIKey: TZFUBYYADABEAV-UHFFFAOYSA-N
SMILES: O=C(C1=NC=CC=C1)N2CCN(CC=3C=CC=CC3)CC2
Biological Activity: Piberaline (EGYT-475; Trelibet) is a psychoactive piperazine derivative with stimulant and antidepressant effects. Piberaline antagonizes Reserpine (HY-N0480)-induced dopamine depletion. Piberaline can be used for research on depression and central nervous system disorders[1][2][3].
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Piberaline | Piberaline (EGYT-475; Trelibet) is a psychoactive piperazine derivative with stimulant and antidepressant effects. Piberaline antagonizes Reserpine (HY-N0480)-induced dopamine depletion. Piberaline can be used for research on depression and central nervous system disorders. | |||||||||||||||||||||
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References
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[1]. D Dauzonne, et al. Synthesis and some CNS activities of new benzofuranylacryloylpiperazines,
European Journal of Medicinal Chemistry, Volume 30, Issue 1, 1995, Pages 53-59. - [2]. Nikonovich T, et al. Mechanochemical C–N Bond-Forming Reactions and Their Application in Pharmaceutical Synthesis. TalTech Press. 2024.
- [3]. Staack RF, et al. Studies on the metabolism and toxicological detection of the new designer drug N-benzylpiperazine in urine using gas chromatography-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2002 Jun 15;773(1):35-46.
Keywords
