41183-02-2
Chemical Structure
OY-101
- CAS No.: 41183-02-2
- Formula:C27H31NO4
- Molecular Weight:433.54
IUPAC Name: 1-(3-(benzyloxy)-4-methoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline
InChIKey: VGJZVOUZZFXQBK-UHFFFAOYSA-N
SMILES: CN1C(CC2=CC=C(OC)C(OCC3=CC=CC=C3)=C2)C4=C(C=C(OC)C(OC)=C4)CC1
Biological Activity: OY-101 is an orally active, potent and specific P-glycoprotein (P-gp) inhibitor. OY-101 can sensitize drug-resistant tumors and effectively reverse tumor multidrug resistance. OY-101 is improvements in water-solubility, cytotoxicity, and reversal activity compared to Tetrandrine (HY-13764)[1].
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OY-101 | OY-101 is an orally active, potent and specific P-glycoprotein (P-gp) inhibitor. OY-101 can sensitize drug-resistant tumors and effectively reverse tumor multidrug resistance. OY-101 is improvements in water-solubility, cytotoxicity, and reversal activity compared to Tetrandrine (HY-13764). | |||||||||||||||||||||
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Keywords