4366-18-1
Chemical Structure
Coumetarol
Synonym(s): Dicumoxane; Ph 137
- CAS No.: 4366-18-1
- Formula:C21H16O7
- Molecular Weight:380.35
IUPAC Name: 3,3'-(2-methoxyethane-1,1-diyl)bis(4-hydroxy-2H-chromen-2-one)
InChIKey: BUCJFFQZPGTGPX-UHFFFAOYSA-N
SMILES: COCC(C1=C(O)C2=CC=CC=C2OC1=O)C3=C(O)C4=CC=CC=C4OC3=O
Biological Activity: Coumetarol (Dicumoxane) is a vitamin K antagonist.
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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Coumetarol | 99.05% | Coumetarol (Dicumoxane) is a vitamin K antagonist. | ||||||||||||||||||||
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10-Hydroxywarfarin | 99.9% | 10-Hydroxywarfarin, a metabolite of (R)-(+)-Warfarin (HY-W015998 ), is a CYP2C9 and vitamin K epoxide reductase complex 1 (VKOR) inhibitor with IC50s of 1.6 µM and 80 ng/mL, respectively. | ||||||||||||||||||||
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α-Glucosidase-IN-28 | α-Glucosidase-IN-28 (Compound 18) is a α-Glucosidase inhibitor (IC50: 0.62 μM, Ki: 3.93 μM). α-Glucosidase-IN-28 binds to α-glucosidase at the original binding site (OBS), and forms multiple hydrophobic interactions with nearby amino acids. α-Glucosidase-IN-28 can be used for research of diabetes and related diseases. | |||||||||||||||||||||
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Phenprocoumon (Standard) | ≥98% | Phenprocoumon (Standard) is the analytical standard of Phenprocoumon. This product is intended for research and analytical applications. Phenprocoumon is a coumarin derivative that acts as a long acting oral anticoagulant and an antagonist of vitamin K. | ||||||||||||||||||||
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Ethyl biscoumacetate | Ethyl biscoumacetate is an anticoagulant and vitamin K antagonist. Ethyl biscoumacetate can be used in the research of experimental venous thrombosis. | |||||||||||||||||||||
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Dicoumarol | 99.89% | Dicoumarol is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively. | ||||||||||||||||||||
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Coumachlor | 99.03% | Coumachlor is an orally active antieoagulant agent. Coumachlor is a vitamin K antagonist. | ||||||||||||||||||||
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(R)-(+)-Warfarin | 99.55% | (R)-(+)-Warfarin is an orally active chiral 4-hydroxycoumarin compound with vitamin K epoxide reductase (VKOR) inhibitory activity and cytochrome P450 substrate activity. (R)-(+)-Warfarin undergoes stereoselective metabolism via CYP1A2 to form 6-Hydroxywarfarin and 8-Hydroxywarfarin, and is metabolized via CYP3A4 to produce 10-Hydroxywarfarin (HY-134999). (R)-(+)-Warfarin can be used for the research of thromboembolic diseases. | ||||||||||||||||||||
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Urease-IN-17 | Urease-IN-17 (9) is a urease inhibitor, with an IC50 of 84 μM. | |||||||||||||||||||||
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