4431-01-0
4431-01-0
Chemical Structure
Ligustilide
- CAS No.: 4431-01-0
- Formula:C12H14O2
- Molecular Weight:190.24
IUPAC Name: (Z)-3-butylidene-4,5-dihydroisobenzofuran-1(3H)-one
InChIKey: IQVQXVFMNOFTMU-FLIBITNWSA-N
SMILES: O=C1O/C(C2=C1C=CCC2)=C\CCC
Biological Activity: Ligustilide is is a bioactive phthalide derivative isolated from Angelica sinensis and Chuanxiong. Ligustilide exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects[1][2][3].
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Ligustilide | 98.06% | Ligustilide is is a bioactive phthalide derivative isolated from Angelica sinensis and Chuanxiong. Ligustilide exhibits neuroprotective, anti-cancer, anti-inflammatory, and vasodilator effects. | ||||||||||||||||||||
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References
- [1]. Eun Sik Choi, et al. Ligustilide attenuates vascular inflammation and activates Nrf2/HO-1 induction and, NO synthesis in HUVECs. Phytomedicine. 2018 Jan 1;38:12-23. [Content Brief]
- [2]. Wu Q, et al. Protective effect of ligustilide against glutamate-induced apoptosis in PC12 cells. Yao Xue Xue Bao. 2015 Feb;50(2):162-8. [Content Brief]
- [3]. Jing Ma, et al. Ligustilide promotes apoptosis of cancer-associated fibroblasts via the TLR4 pathways. Food Chem Toxicol. 2020 Jan;135:110991. [Content Brief]
Keywords
