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  5. (E)-Ligustilide

(E)-Ligustilide is isolated from Angelica sinensis and has nephroprotective effects.

For research use only. We do not sell to patients.

(E)-Ligustilide Chemical Structure

(E)-Ligustilide Chemical Structure

CAS No. : 81944-08-3

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Description

(E)-Ligustilide is isolated from Angelica sinensis and has nephroprotective effects[1].

In Vitro

(E)-Ligustilide (50 μM; 24-72 hours) decreases HK-2 cell survival to 86%, to 67% and to 49% for 24, 48 or 72 hours incubation, respectively[1].
(E)-Ligustilide (50 μM; 48-72 hours) alone decreases the metabolic activity to 87±6% and 71±8% after 48 and 72 h incubation, respectively, as compared to the control condition in HK-2 cells[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: HK-2 cell
Concentration: 50 μM
Incubation Time: 24 hours, 48 hours and 72 hours
Result: Decreased cell survival as a dose-dependent manner.
Molecular Weight

190.24

Formula

C12H14O2

CAS No.
SMILES

O=C1O/C(C2=C1C=CCC2)=C/CCC.[(E)]

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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(E)-Ligustilide
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HY-N0401B
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