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Ligustilide 

Cat. No.: HY-N0401
Handling Instructions

Ligustilide is an effective constituent extracted from Angelica sinensis.

For research use only. We do not sell to patients.
Ligustilide Chemical Structure

Ligustilide Chemical Structure

CAS No. : 4431-01-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO $198 In-stock
5 mg $180 In-stock
10 mg $280 In-stock
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

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Description

Ligustilide is an effective constituent extracted from Angelica sinensis. IC50 value: Target: In vitro: To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide [1]. In vivo:

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 5.2565 mL 26.2826 mL 52.5652 mL
5 mM 1.0513 mL 5.2565 mL 10.5130 mL
10 mM 0.5257 mL 2.6283 mL 5.2565 mL
References
Molecular Weight

190.24

Formula

C₁₂H₁₄O₂

CAS No.

4431-01-0

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Ligustilide
Cat. No.:
HY-N0401
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