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Ligustilide 

Cat. No.: HY-N0401 Purity: 98.49%
Handling Instructions

Ligustilide is an effective constituent extracted from Angelica sinensis.

For research use only. We do not sell to patients.

Ligustilide Chemical Structure

Ligustilide Chemical Structure

CAS No. : 4431-01-0

Size Price Stock Quantity
1 mg USD 70 In-stock
Estimated Time of Arrival: December 31
5 mg USD 216 In-stock
Estimated Time of Arrival: December 31
10 mg USD 336 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Ligustilide:

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Description

Ligustilide is an effective constituent extracted from Angelica sinensis. IC50 value: Target: In vitro: To investigate the neuroprotective of ligustilide (LIG) against glutamate-induced apoptosis of PC12 cells, cell viability were examined by MTT assay. Pretreatment with ligustilide (1, 5, 15 μmol · L(-1)) significantly improved cell viability. The apoptosis rate in glutamate-induced PC12 cells was 13.39%, and decreased in the presence of ligustilide (1, 5, 15 μmol · L(-1)) by 9.06%, 6.48%, 3.82%, separately. Extracellular accumulation of Ca2+ induced by glutamate were significantly reduced by ligustilide [1]. In vivo:

Molecular Weight

190.24

Formula

C₁₂H₁₄O₂

CAS No.

4431-01-0

SMILES

O=C1O/C(C2=C1C=CCC2)=C\CCC

Shipping

Room temperature in continental US; may vary elsewhere

Storage

-20°C, stored under nitrogen

*The compound is unstable in solutions, freshly prepared is recommended.

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (262.83 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2565 mL 26.2826 mL 52.5652 mL
5 mM 1.0513 mL 5.2565 mL 10.5130 mL
10 mM 0.5257 mL 2.6283 mL 5.2565 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
Ligustilide
Cat. No.:
HY-N0401
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