445000-45-3
Chemical Structure
BBT
- CAS No.: 445000-45-3
- Formula:C18H12BrNO2S
- Molecular Weight:386.26
IUPAC Name: N-(2-benzoylphenyl)-5-bromothiophene-2-carboxamide
InChIKey: FCSCANHTNNHZOH-UHFFFAOYSA-N
SMILES: C1(=CC=C(Br)S1)C(=O)NC1=CC=CC=C1C(C1C=CC=CC=1)=O
Biological Activity: BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ (HY-13753))-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathway[1].
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BBT | 99.71% | BBT is an enhancer of impaired glucose-stimulated insulin secretion (GSIS). BBT exhibits anti-hyperglycemia activity, and protects β-cells from cytokine- or streptozotocin (STZ (HY-13753))-induced cell death in type 2 diabetes models. BBT acts function via cAMP/PKA and long-lasting (L-type) voltage-dependent Ca2+ channel/CaMK2 pathway. | ||||||||||||||||||||
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Keywords
