452072-20-7
Chemical Structure
SPP-DM1
- CAS No.: 452072-20-7
- Formula:C44H59ClN4O14S2
- Molecular Weight:967.54
IUPAC Name: 2,5-dioxopyrrolidin-1-yl 4-((3-(((S)-1-(((14S,16S,32S,33S,2R,4S,10E,12E,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-3-oxopropyl)disulfanyl)pentanoate
InChIKey: ZMOVORWFEGTIJA-MUZJBSEYSA-N
SMILES: C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCSSC(C)CCC(ON5C(CCC5=O)=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
Biological Activity: SPP-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
SPP-DM1 | 98.69% | SPP-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.91
HY-126493A(R)-DM4-SPDP -
Similarity Score 0.90
HY-12460SPDB-DM4 -
Similarity Score 0.85
HY-101141sulfo-SPDB-DM4 -
Similarity Score 0.82
HY-100128RDM1-SMe (Standard) -
Similarity Score 0.82
HY-130081DM3-SMe -
Similarity Score 0.81
HY-128960DBA-DM4 -
Similarity Score 0.80
HY-100504S-methyl DM1 -
Similarity Score 0.80
HY-130080DM3 -
Similarity Score 0.80
HY-128954Sulfo-PDBA-DM4 -
Explore the MedChemAI to find more analogs
