458151-34-3
458151-34-3
Chemical Structure
Thalidomide-benzo
- CAS No.: 458151-34-3
- Formula:C17H12N2O4
- Molecular Weight:308.29
IUPAC Name: 2-(2,6-dioxopiperidin-3-yl)-1H-benzo[f]isoindole-1,3(2H)-dione
InChIKey: WEZVWZZGZAYKRL-UHFFFAOYSA-N
SMILES: O=C1NC(C(CC1)N2C(C3=CC4=C(C=C3C2=O)C=CC=C4)=O)=O
Biological Activity: Thalidomide-benzo hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-benzo can be connected to the ligand for protein by a linker to form PROTACs[1].
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Thalidomide-benzo | Thalidomide-benzo hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-benzo can be connected to the ligand for protein by a linker to form PROTACs. | |||||||||||||||||||||
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References
Keywords
