4604-41-5
4604-41-5
Chemical Structure
3,3'-Diiodo-L-thyronine
Synonym(s): 3,3'-T2
- CAS No.: 4604-41-5
- Formula:C15H13I2NO4
- Molecular Weight:525.08
IUPAC Name: (S)-2-amino-3-(4-(4-hydroxy-3-iodophenoxy)-3-iodophenyl)propanoic acid
InChIKey: CPCJBZABTUOGNM-LBPRGKRZSA-N
SMILES: N[C@@H](CC1=CC=C(OC2=CC=C(O)C(I)=C2)C(I)=C1)C(O)=O
Biological Activity: 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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3,3'-Diiodo-L-thyronine | 96.33% | 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity. | ||||||||||||||||||||
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3,3'-Diiodo-L-thyronine (Standard) | 95.29% | 3,3'-Diiodo-L-thyronine (Standard) is the analytical standard of 3,3'-Diiodo-L-thyronine. This product is intended for research and analytical applications. 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity. | ||||||||||||||||||||
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3,3'-Diiodo-L-thyronine-13C6 | 3,3'-Diiodo-L-thyronine-13C6 is the 13C labeled 3,3'-Diiodo-L-thyronine. 3,3'-Diiodo-L-thyronine (3,3'-T2) is an endogenous metabolite of thyroid hormone. 3,3'-Diiodo-L-thyronine significantly enhances COX activity. | |||||||||||||||||||||
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3,5,3'-Triiodo-D-thyronine | 95.22% | 3,5,3'-Triiodo-D-thyronine, a thyroid hormone, is less effective than 3,5,3'-Triiodo-T-thyronine in normalizing the increased plasma creatine phosphokinase (CPK) activity. | ||||||||||||||||||||
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3-Iodo-L-thyronine-13C6 | 3-Iodo-L-thyronine-13C6 is the 13C-labeled 3-Iodo-L-thyronine (HY-W588264). 3-Iodo-L-thyronine (3-Monoiodothyronine) is an endogenous iodothyronine thyroid hormone metabolite. 3-Iodo-L-thyronine can be used for research on differentiated thyroid cancer. | |||||||||||||||||||||
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Liothyronine (Standard) | 98.57% | Liothyronine (Standard) is the analytical standard of Liothyronine. This product is intended for research and analytical applications. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively. | ||||||||||||||||||||
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Liothyronine-13C9,15N | Liothyronine-13C9,15N is the 13C and 15N labeled Liothyronine. Liothyronine is an active form of thyroid hormone. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively. | |||||||||||||||||||||
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Liothyronine-13C6-1 | 98.06% | Liothyronine-13C6-1 is a 13C-labeled Liothyronine. Liothyronine is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively. | ||||||||||||||||||||
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Reverse T3-13C6 hydrochloride | 96% | Reverse T3-13C6 (hydrochloride) is the 13C labeled Reverse T3. | ||||||||||||||||||||
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Reverse T3 (Standard) | 95.63% | Reverse T3 (Standard) is the analytical standard of Reverse T3. This product is intended for research and analytical applications. Reverse T3 is a thyroid hormone that can be generated by deiodination of the prohormone thyroxine. Reverse T3 inhibits the increase of sodium current generated by other thyroid hormone analogs in neonatal rat myocytes. | ||||||||||||||||||||
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3-Iodo-L-thyronine | 99.79% | 3-Iodo-L-thyronine (3-Monoiodothyronine) is an endogenous iodothyronine thyroid hormone metabolite. 3-Iodo-L-thyronine can be used for research on differentiated thyroid cancer. | ||||||||||||||||||||
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Reverse T3-13C6 | 3,3',5'-Triiodo-L-thyronine-13C6 is 13C labeled 3,3',5'-Triiodo-L-thyronine. | |||||||||||||||||||||
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References
- [1]. Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3'-diiodo-L-thyronine (3,3'-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88. [Content Brief]
- [2]. Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine. Mol Cell Endocrinol. 1994 Feb;99(1):89-94. [Content Brief]
