475479-34-6
Chemical Structure
Aleglitazar
Synonym(s): R1439; RO0728804
- CAS No.: 475479-34-6
- Formula:C24H23NO5S
- Molecular Weight:437.51
IUPAC Name: (S)-2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)benzo[b]thiophen-7-yl)propanoic acid
InChIKey: DAYKLWSKQJBGCS-NRFANRHFSA-N
SMILES: CC1=C(CCOC2=CC=C(C[C@@H](C(O)=O)OC)C3=C2C=CS3)N=C(C4=CC=CC=C4)O1
Biological Activity: Aleglitazar (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes[1].
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Aleglitazar | 99.74% | Aleglitazar (R1439) is a potent dual PPARα/γ agonist, with IC50s of 38 nM and 19 nM for human PPARa and PPARγ, respectively. Aleglitazar can be used for the research of type II diabetes. | ||||||||||||||||||||
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Deutaleglitazar | Deutaleglitazar (Aleglitazar-d2) is a agonist of dual peroxisome proliferatory activating receptor (PPARα and PPARγ). | |||||||||||||||||||||
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Keywords