4818-19-3
4818-19-3
Chemical Structure
IIIM-1270
- CAS No.: 4818-19-3
- Formula:C12H11NO2S
- Molecular Weight:233.29
IUPAC Name: (E)-5-(2,4-dimethylbenzylidene)thiazolidine-2,4-dione
InChIKey: KFYPWWDPFGBNDO-UXBLZVDNSA-N
SMILES: CC1=CC=C(/C=C2SC(NC/2=O)=O)C(C)=C1
Biological Activity: IIIM-1270is a NLRP3 inflammasome inhibitor. IIIM-1270 inhibits IL-1β release in mouse macrophages (J774A.1 cells) (IC50 = 3.5 μM) and significantly reduced the protein expression level of mature IL-1β. IIIM-1270 can be used for the study of inflammation[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
IIIM-1270 | 98.78% | IIIM-1270is a NLRP3 inflammasome inhibitor. IIIM-1270 inhibits IL-1β release in mouse macrophages (J774A.1 cells) (IC50 = 3.5 μM) and significantly reduced the protein expression level of mature IL-1β. IIIM-1270 can be used for the study of inflammation. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
