IIIM-1270
Based on 1 Customer Validation
IIIM-1270is a NLRP3 inflammasome inhibitor. IIIM-1270 inhibits IL-1β release in mouse macrophages (J774A.1 cells) (IC50 = 3.5 μM) and significantly reduced the protein expression level of mature IL-1β. IIIM-1270 can be used for the study of inflammation.
For research use only. We do not sell to patients.
- Purity: 98.78%
- CAS No.: 4818-19-3
- Formula: C12H11NO2S
- Molecular Weight:233.29
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
-
Bioactive Compound Library Max
HY-L181
-
Bioactive Compound Library
HY-L001
-
Immunology/Inflammation Compound Library
HY-L007
-
NF-κB Signaling Compound Library
HY-L014
-
Antioxidant Compound Library
HY-L037
-
Differentiation Inducing Compound Library
HY-L038
-
Oxygen Sensing Compound Library
HY-L045
-
Pyroptosis Compound Library
HY-L059
-
Angiogenesis-Related Compound Library
HY-L088
-
Antidepressant Compound Library
HY-L108
-
Pain-Related Compound Library
HY-L139
-
Membrane Receptor-targeted Compound Library
HY-L150
-
Autoimmune Disease Compound Library
HY-L156
-
Cytokine Inhibitors Library
HY-L161
-
Macrophage Related Compound Library
HY-L174
-
Inflammasomes related Compound Library
HY-L175
-
Radioprotector Library
HY-L178
-
MCE Bioactive Compound Library
HY-L001V
-
Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library
HY-L199
-
High-Throughput Bioactive Compound Library
HY-L205
-
Pattern Recognition Receptors Library
HY-L237
Biological Activity
Chemical Information
-
CAS No. 4818-19-3
-
Appearance Powder
-
Molecular Weight 233.29
-
Formula C12H11NO2S
-
Color off-white
-
SMILES
CC1=CC=C(/C=C2SC(NC/2=O)=O)C(C)=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (107.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (272 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.2865 mL | 21.4326 mL | 42.8651 mL | 107.1628 mL |
| 5 mM | 0.8573 mL | 4.2865 mL | 8.5730 mL | 21.4326 mL | |
| 10 mM | 0.4287 mL | 2.1433 mL | 4.2865 mL | 10.7163 mL | |
| 15 mM | 0.2858 mL | 1.4288 mL | 2.8577 mL | 7.1442 mL | |
| 20 mM | 0.2143 mL | 1.0716 mL | 2.1433 mL | 5.3581 mL | |
| 25 mM | 0.1715 mL | 0.8573 mL | 1.7146 mL | 4.2865 mL | |
| 30 mM | 0.1429 mL | 0.7144 mL | 1.4288 mL | 3.5721 mL | |
| 40 mM | 0.1072 mL | 0.5358 mL | 1.0716 mL | 2.6791 mL | |
| 50 mM | 0.0857 mL | 0.4287 mL | 0.8573 mL | 2.1433 mL | |
| 60 mM | 0.0714 mL | 0.3572 mL | 0.7144 mL | 1.7860 mL | |
| 80 mM | 0.0536 mL | 0.2679 mL | 0.5358 mL | 1.3395 mL | |
| 100 mM | 0.0429 mL | 0.2143 mL | 0.4287 mL | 1.0716 mL |
IIIM-1270 Related Classifications
HY-133133 Related Classifications
Powered by Bioz