494830-67-0
494830-67-0
Chemical Structure
NIC3
- CAS. Nr.: 494830-67-0
- Formula:C26H36N2O4
- Molecular Weight:440.58
IUPAC Name: N,N'-(ethane-1,2-diyl)bis(2-(4-(tert-butyl)phenoxy)acetamide)
InChIKey: ZVSHISOEPMAPLF-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC=C(OCC(NCCNC(COC2=CC=C(C(C)(C)C)C=C2)=O)=O)C=C1
Biological Activity: NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity[1].
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NIC3 | 99.80% | NIC3 is a selective nucleus accumbens-associated protein-1 (NAC1) inhibitor, binds to the conserved Leu-90 of NAC1, prevents its homodimerization, and leads to proteasomal NAC1 degradation. Anti-cancer activity. | ||||||||||||||||||||
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References
Keywords
