500577-51-5
500577-51-5
Chemical Structure
Cyclo(-RGDfK) TFA
- CAS No.: 500577-51-5
- Formula:C29H42F3N9O9
- Molecular Weight:717.69
InChIKey: WHCQIPJAWCYHFT-HXSCNMCGSA-N
SMILES: O=C(O)C(F)(F)F.O=C([C@H](CCCCN)NC([C@@H](CC1=CC=CC=C1)NC([C@H](CC(O)=O)NC(CN2)=O)=O)=O)N[C@@H](CCCNC(N)=N)C2=O
Biological Activity: Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM[1]. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface[3].
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Cyclo(-RGDfK) TFA | 99.61% | Cyclo(-RGDfK) TFA is a potent and selective inhibitor of the αvβ3 integrin, with an IC50 of 0.94 nM. Cyclo(-RGDfK) TFA potently targets tumor microvasculature and cancer cells through the specific binding to the αvβ3 integrin on the cell surface. | ||||||||||||||||||||
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