501662-77-7
501662-77-7
Chemical Structure
GQC-05
Synonym(s): NSC 338258
- CAS No.: 501662-77-7
- Formula:C21H23N3O
- Molecular Weight:333.43
InChIKey: FGFDMBHOYCMKEJ-UHFFFAOYSA-N
SMILES: CN(C)CCOC1=CC=C2C(C(C(C)=C3C(C=CN=C3)=C4C)=C4N2)=C1
Biological Activity: GQC-05 (NSC338258), Ellipticine (HY-15753) derivative, is potent and selective c-Myc G-quadruplex ( c-Myc G4) stabilizer with KD values of 0.1-1.43 μM. GQC-05 can reduce Myc expression and induce cancer cells apoptosis. GQC-05 can be used for the research of cancer, such as Burkitt lymphoma[1].
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GQC-05 | GQC-05 (NSC338258), Ellipticine (HY-15753) derivative, is potent and selective c-Myc G-quadruplex ( c-Myc G4) stabilizer with KD values of 0.1-1.43 μM. GQC-05 can reduce Myc expression and induce cancer cells apoptosis. GQC-05 can be used for the research of cancer, such as Burkitt lymphoma. | |||||||||||||||||||||
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References
Keywords
