511-45-5
511-45-5
Chemical Structure
Pridinol
- CAS 番号: 511-45-5
- Formula:C20H25NO
- Molecular Weight:295.42
IUPAC Name: 1,1-diphenyl-3-(piperidin-1-yl)propan-1-ol
InChIKey: RQXCLMGKHJWMOA-UHFFFAOYSA-N
SMILES: OC(C1=CC=CC=C1)(C2=CC=CC=C2)CCN3CCCCC3
Biological Activity: Pridinol is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR)-directed muscle relaxant. Pridinol reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases[1][2].
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Pridinol | Pridinol is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR)-directed muscle relaxant. Pridinol reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases. | |||||||||||||||||||||
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Pridinol-d5 | Pridinol-d5 is deuterium labeled Pridinol (HY-B1343A). Pridinol is an orally active, blood-brain permeable, muscarinic acetylcholine receptor (mAChR)-directed muscle relaxant. Pridinol reduces the conduction of impulses to spinal motor neurons and exerts muscle relaxant activity. Pridinol inhibits skeletal muscle contractures in diseases of both central and peripheral origin and can be used in research in the field of musculoskeletal diseases. | |||||||||||||||||||||
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References
- [1]. Richter M, et al. Pharmacokinetics of oral pridinol: Results of a randomized, crossover bioequivalence trial in healthy subjects. Int J Clin Pharmacol Ther. 2021 Jun;59(6):471-477. [Content Brief]
- [2]. Lauricella L, et al. Effectiveness rehabilitative therapy and Pridinol Mesylate in low back pain. Front Med (Lausanne) . 2025 Jan 22;11:1470996. [Content Brief]
