5122-36-1
5122-36-1
Chemical Structure
FAPy-adenine
- CAS No.: 5122-36-1
- Formula:C5H7N5O
- Molecular Weight:153.14
IUPAC Name: N-(4,6-diaminopyrimidin-5-yl)formamide
InChIKey: MVYUVUOSXNYQLL-UHFFFAOYSA-N
SMILES: O=CNC1=C(N)N=CN=C1N
Biological Activity: FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases[1][2][3].
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FAPy-adenine | 99.86% | FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases. | ||||||||||||||||||||
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FAPy-adenine (Standard) | ≥98% | FAPy-adenine (Standard) is the analytical standard of FAPy-adenine. This product is intended for research and analytical applications. FAPy-adenine is an oxidized DNA base. Fapy-adenine shows an increased trend levels in the Alzheimer's disease brain. Oxidized nucleosides are biochemical markers for tumors, aging, and neurodegenerative diseases. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.73
HY-W653715Formylaminopyrimidine -
Similarity Score 0.70
HY-W539745R2,4,6-Triamino-5-nitrosopyrimidine (Standard) -
Similarity Score 0.70
HY-1031728-Aminoadenine -
Similarity Score 0.69
HY-341885-Bromo-6-chloro-4-pyrimidinamine -
Similarity Score 0.69
HY-D10612,4,5,6-Tetraaminopyrimidine -
Similarity Score 0.68
HY-W7777574,5-Diamino-6-hydroxypyrimidine-13C,15N -
Similarity Score 0.68
HY-150859HDAC ligand-1 -
Similarity Score 0.68
HY-Y0215R5-Azacytosine (Standard) -
Similarity Score 0.68
HY-W0019874,6-Dichloropyrimidin-5-amine -
Explore the MedChemAI to find more analogs
References
- [1]. Gabbita SP, et al. Increased nuclear DNA oxidation in the brain in Alzheimer's disease. [Content Brief]
- [2]. Cysewski P, et al. Theoretical description of the coding potential of diamino-5-formamidopyrimidines. Z Naturforsch C J Biosci. 1999 Mar-Apr;54(3-4):239-45. [Content Brief]
- [3]. Lee SH, et al. A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection. Rapid Commun Mass Spectrom. 2004;18(9):973-7. [Content Brief]
