515-69-5
515-69-5
Chemical Structure
alpha-Bisabolol
- CAS No.: 515-69-5
- Formula:C15H26O
- Molecular Weight:222.37
IUPAC Name: (R)-6-methyl-2-((R)-4-methylcyclohex-3-en-1-yl)hept-5-en-2-ol
InChIKey: RGZSQWQPBWRIAQ-LSDHHAIUSA-N
SMILES: C/C(C)=C\CC[C@@](O)([C@@H]1CCC(C)=CC1)C
Biological Activity: alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
alpha-Bisabolol | 80.0% | alpha-Bisabolol, an orally active sesquiterpene alcohol, induces cell cycle arrest, mitochondrial apoptosis and inhibition of PI3K/Akt signalling pathways. alpha-Bisabolol exerts a protective action against Cisplatin (HY-17394)-induced nephrotoxicity by mitigating inflammation and oxidative stress through the inhibition of NFκB activation. alpha-Bisabolol exhibits anti-inflammatory, analgesic, antibiotic and anticancer activities. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(-)-α-Eudesmol | 93.98% | (-)-α-Eudesmol is a diterpene dialdehyde that can be isolated from Porella. α-eudesmol has a protective effect against acute brain injury induced by diethylnitrosamine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Neroplomacrol | Neroplomacrol is a sesquiterpenoid and heterocyclic farnesol derivative that occurs in Dalbergia tonkinensis. Neroplomacrol serves as a chemotaxonomic and biochemical marker for Fabaceae. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
cis-Nerolidol (Standard) | ≥98% | cis-Nerolidol (Standard) is the analytical standard of cis-Nerolidol. This product is intended for research and analytical applications. cis-Nerolidol is a sesquiterpene alcohol that can be found in various plants. cis-Nerolidol exhibits antioxidant and antibacterial activities. cis-Nerolidol can also potentiate the action of antibiotics. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nerolidol (Standard) | 98.44% | Nerolidol (Standard) is the analytical standard of Nerolidol. This product is intended for research and analytical applications. Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
trans-Nerolidol (Standard) | 94.58% | trans-Nerolidol (Standard) is the analytical standard of trans-Nerolidol. This product is intended for research and analytical applications. trans-Nerolidol improves the anti-proliferative effect of Doxorubicin (DOX) (HY-15142A) against intestinal cancer and breast cancer cells in vitro. trans-Nerolidol increases accumulation of DOX inside cells in vitro. trans-Nerolidol activates apoptosis in vivo. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Levomenol | 99.22% | Levomenol ((-)-α-Bisabolol), a monocyclic sesquiterpene alcohol, exerts antioxidant, anti-inflammatory, and anti-apoptotic activities. Levomenol also has neuroprotective effects and prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice. Levomenol attenuates nociceptive behaviour and central sensitisation in a rodent model of trigeminal neuropathic pain. Orally active. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Nephthenol | Nephthenol is a terpenoid that can be isolated from Nephthea brassica. Nephthenol exhibits cytotoxicity in cells A549, HT-29, KB and P-388 with IC50s of 2.72, 3.01, 1.84, and 0.42 µg/mL, respectively. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
3,4-Dihydroxybisabola-1,10-diene | 3,4-Dihydroxybisabola-1,10-diene is a Sesquiterpenoids product that can be isolated from the rhizomes of Curcuma xanthorrhiza Roxb. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Valerianol | Valerianol is a sesquiterpene alcohol with anticancer, antibacterial, and antiviral activities. Valerianol selectively inhibits TPA (HY-18739)-induced Epstein-Barr virus early antigen (EBV-EA) activation (IC50=300 μM). Valerianol inhibits tumor promoter-mediated EBV-EA activation and also inhibits pathogenic bacteria such as Staphylococcus aureus. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
β-Bisabolol | β-Bisabolol is a potent anti-inflammatory agent that can be found in cotton gin trash. β-Bisabolol inhibits the production of nitric oxide (NO), pGE2, TNF-α, IL-6, and IL-8 in LPS (HY-D1056)-stimulated macrophages and fibroblast cells. β-Bisabolol can be used for the research on inflammatory conditions. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Wu S, et al. Anticancer effects of α-Bisabolol in human non-small cell lung carcinoma cells are mediated via apoptosis induction, cell cycle arrest, inhibition of cell migration and invasion and upregulation of P13K/AKT signalling pathway. J BUON. 2018 Sep-Oct;23(5):1407-1412. [Content Brief]
- [2]. Nur Elena Zaaba, et al. The Nephroprotective Effects of α-Bisabolol in Cisplatin-Induced Acute Kidney Injury in Mice. Biomedicines. 2022 Apr 3;10(4):842. [Content Brief]
