51551-29-2
51551-29-2
Chemical Structure
Neoechinulin A
- CAS No.: 51551-29-2
- Formula:C19H21N3O2
- Molecular Weight:323.39
IUPAC Name: (S,Z)-3-methyl-6-((2-(2-methylbut-3-en-2-yl)-1H-indol-3-yl)methylene)piperazine-2,5-dione
InChIKey: MYRPIYZIAHOECW-SAIXKJTDSA-N
SMILES: C=CC(C)(C)C1=C(C2=CC=CC=C2N1)/C=C3C(N[C@H](C(N/3)=O)C)=O
Biological Activity: Neoechinulin A is an isoprenyl indole alkaloid that exhibits scavenging, neurotrophic factor-like, and anti-apoptotic activities. Neoechinulin A induces memory improvements and antidepressant-like effects in mice[1][2].
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Neoechinulin A | 98.0% | Neoechinulin A is an isoprenyl indole alkaloid that exhibits scavenging, neurotrophic factor-like, and anti-apoptotic activities. Neoechinulin A induces memory improvements and antidepressant-like effects in mice. | ||||||||||||||||||||
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References
- [1]. Humbert M, et al. Masitinib combined with standard gemcitabine chemotherapy: in vitro and in vivo studies in human pancreatic tumour cell lines and ectopic mouse model. PLoS One. 2010;5(3):e9430. Published 2010 Mar 4. [Content Brief]
- [2]. Kim KS, et al. Anti-inflammatory effect of neoechinulin a from the marine fungus Eurotium sp. SF-5989 through the suppression of NF-кB and p38 MAPK Pathways in lipopolysaccharide-stimulated RAW264.7 macrophages. Molecules. 2013;18(11):13245-13259. Publish [Content Brief]
Keywords
