550-70-9
550-70-9
Chemical Structure
Triprolidine hydrochloride
- CAS No.: 550-70-9
- Formula:C19H23ClN2
- Molecular Weight:314.85
IUPAC Name: (E)-2-(3-(pyrrolidin-1-yl)-1-(p-tolyl)prop-1-en-1-yl)pyridine hydrochloride
InChIKey: WYUYEJNGHIOFOC-NWBUNABESA-N
SMILES: CC1=CC=C(/C(C2=NC=CC=C2)=C\CN3CCCC3)C=C1.[H]Cl
Biological Activity: Triprolidine hydrochloride is an orally active histamine H1 antagonist. Triprolidine hydrochloride has the function of spinal cord motor and sensory block. Triprolidine hydrochloride can be used for the research of allergic rhinitis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Triprolidine hydrochloride | 99.76% | Triprolidine hydrochloride is an orally active histamine H1 antagonist. Triprolidine hydrochloride has the function of spinal cord motor and sensory block. Triprolidine hydrochloride can be used for the research of allergic rhinitis. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
(E/Z)-Triprolidine-d8 hydrochloride | (E/Z)-Triprolidine-d8 (hydrochloride) is the deuterium labeled (E/Z)-Triprolidine hydrochloride. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Szeberényi JB, et, al. Inhibition of effects of endogenously synthesized histamine disturbs in vitro human dendritic cell differentiation. Immunol Lett. 2001 Apr 2;76(3):175-82. [Content Brief]
- [2]. Tzeng JI, et, al. Spinal sensory and motor blockade by intrathecal doxylamine and triprolidine in rats. J Pharm Pharmacol. 2018 Dec;70(12):1654-1661. [Content Brief]
- [3]. Deal DL, Chandrasurin P, Shockcor J, Minick DJ, Findlay JW, McNulty MJ. Disposition and metabolism of triprolidine in mice. Drug Metab Dispos. 1992 Nov-Dec;20(6):920-7. [Content Brief]
