1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
  2. Histamine Receptor
  3. Triprolidine hydrochloride

Triprolidine hydrochloride 

Cat. No.: HY-B1808A
Handling Instructions

Triprolidine is an oral active, first-generation histamine H1-receptor antagonist. Triprolidine can be used for the research of allergic rhinitis. triprolidine exhibits spinal motor and sensory block in rats.

For research use only. We do not sell to patients.

Triprolidine hydrochloride Chemical Structure

Triprolidine hydrochloride Chemical Structure

CAS No. : 550-70-9

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Description

Triprolidine is an oral active, first-generation histamine H1-receptor antagonist. Triprolidine can be used for the research of allergic rhinitis. triprolidine exhibits spinal motor and sensory block in rats[1][2][3].

IC50 & Target[1]

H1 Receptor

 

In Vivo

Triprolidine (292.81-1467.20 μg/kg; intrathecal injection) produces a dose-dependent effect of spinal motor and sensory block in rats[3].

Animal Model: Male Sprague-Dawley rat (300-350 g)[3]
Dosage: 292.81 μg/kg, 488.02 μg/kg, 733.60μg/kg, 1098.83 μg/kg, 1467.20 μg/kg
Administration: Intrathecal injection
Result: Elicited a dose-dependent spinal block.
Molecular Weight

314.85

Formula

C₁₉H₂₃ClN₂

CAS No.

550-70-9

SMILES

CC1=CC=C(/C(C2=NC=CC=C2)=C\CN3CCCC3)C=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

TriprolidineHistamine Receptorantihistamineallergic rhinitisspinalmotorsensoryInhibitorinhibitorinhibit

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Triprolidine hydrochloride
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HY-B1808A
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