1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
  2. Histamine Receptor
  3. Triprolidine hydrochloride monohydrate

Triprolidine hydrochloride monohydrate 

Cat. No.: HY-B1301 Purity: 99.87%
Handling Instructions

Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats.

For research use only. We do not sell to patients.

Triprolidine hydrochloride monohydrate Chemical Structure

Triprolidine hydrochloride monohydrate Chemical Structure

CAS No. : 6138-79-0

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10 mM * 1 mL in DMSO USD 55 In-stock
Estimated Time of Arrival: December 31
10 mg USD 50 In-stock
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25 mg USD 95 In-stock
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50 mg USD 162 In-stock
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100 mg USD 275 In-stock
Estimated Time of Arrival: December 31
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Triprolidine hydrochloride monohydrate, a first-generation antihistamine, is an oral active histamine H1 antagonist. Triprolidine hydrochloride monohydrate can be used for the research of allergic rhinitis. Triprolidine hydrochloride monohydrate exhibits spinal motor and sensory block in rats[1][2][3].

IC50 & Target[1]

H1 Receptor

 

In Vivo

Triprolidine hydrochloride monohydrate (292.81-1467.20 μg/kg; intrathecal injection) produces a dose-dependent effect of spinal motor and sensory block in rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rat (300-350 g)[3]
Dosage: 292.81 μg/kg, 488.02 μg/kg, 733.60μg/kg, 1098.83 μg/kg, 1467.20 μg/kg
Administration: Intrathecal injection
Result: Elicited a dose-dependent spinal block.
Molecular Weight

332.87

Formula

C₁₉H₂₅ClN₂O

CAS No.

6138-79-0

SMILES

CC1=CC=C(/C(C2=NC=CC=C2)=C\CN3CCCC3)C=C1.[H]Cl.[H]O[H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
References
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Keywords:

Triprolidine hydrochlorideHistamine Receptorantihistamineallergic rhinitisspinal motorsensoryInhibitorinhibitorinhibit

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Product Name:
Triprolidine hydrochloride monohydrate
Cat. No.:
HY-B1301
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