558447-26-0
Chemical Structure
Mavorixafor
Synonym(s): AMD-070; AMD-11070
- CAS No.: 558447-26-0
- Formula:C21H27N5
- Molecular Weight:349.47
IUPAC Name: (S)-N1-((1H-benzo[d]imidazol-2-yl)methyl)-N1-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine
InChIKey: WVLHHLRVNDMIAR-IBGZPJMESA-N
SMILES: NCCCCN(CC1=NC2=C(N1)C=CC=C2)[C@@H]3C4=C(CCC3)C=CC=N4
Biological Activity: Mavorixafor (AMD-070) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively. Mavorixafor can be used for the study of WHIM syndrome[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Mavorixafor | 99.66% | Mavorixafor (AMD-070) is a potent, selective and orally available CXCR4 antagonist, with an IC50 value of 13 nM against CXCR4 125I-SDF binding, and also inhibits the replication of T-tropic HIV-1 (NL4.3 strain) in MT-4 cells and PBMCs with an IC50 of 1 and 9 nM, respectively. Mavorixafor can be used for the study of WHIM syndrome. | ||||||||||||||||||||
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Similarity Score 0.98
HY-50101CMavorixafor hydrochloride -
Similarity Score 0.96
HY-50101AMavorixafor trihydrochloride -
Similarity Score 0.67
HY-115493TIQ-15 -
Similarity Score 0.64
HY-144286CXCR4 antagonist 3 -
Similarity Score 0.52
HY-144285CXCR4 antagonist 4 -
Similarity Score 0.51
HY-146372CXCR4 antagonist 5 -
Similarity Score 0.51
HY-110105NS8593 hydrochloride -
Similarity Score 0.50
HY-137952NS8593 -
Similarity Score 0.50
HY-130203Dopamine D4R antagonist-1 -
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