56-47-3
56-47-3
Chemical Structure
Deoxycorticosterone acetate
Synonym(s): 11-Deoxycorticosterone acetate; DOC acetate; Cortexone acetate
- CAS No.: 56-47-3
- Formula:C23H32O4
- Molecular Weight:372.50
IUPAC Name: 2-((8S,9S,10R,13S,14S,17S)-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl acetate
InChIKey: VPGRYOFKCNULNK-ACXQXYJUSA-N
SMILES: C[C@@]12[C@@H](C(COC(C)=O)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC2)=O
Biological Activity: Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria[1][2].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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Deoxycorticosterone acetate | 99.87% | Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria. | ||||||||||||||||||||
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Deoxycorticosterone acetate (Standard) | 99.30% | Deoxycorticosterone acetate (Standard) is the analytical standard of Deoxycorticosterone acetate. This product is intended for research and analytical applications. Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria. | ||||||||||||||||||||
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Desoxycorticosterone pivalate | 99.62% | Desoxycorticosterone pivalate (DOCP) is a mineralocorticoid hormone and an analog of Desoxycorticosterone. Desoxycorticosterone pivalate is used for the management of canine hypoadrenocorticism. | ||||||||||||||||||||
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Progesterone carboxylic acid (Standard) | ≥98% | Progesterone carboxylic acid (Standard) is the analytical standard of Progesterone carboxylic acid (HY-108409). This product is intended for research and analytical applications. Progesterone carboxylic acid (Testosterone-17β-carboxylic acid) is an androstenedione analogue. Progesterone carboxylic acid can conjugate with 20-mer peptide nucleic acid (PNA) and the conjugate has superior binding capacity on complementary DNA. Progesterone carboxylic acid can be used for cancers and type 2 diabetes (T2D) research. | ||||||||||||||||||||
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Deoxycorticosterone (Standard) | 99.83% | Deoxycorticosterone (Standard) is the analytical standard of Deoxycorticosterone. This product is intended for research and analytical applications. Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. | ||||||||||||||||||||
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21-Acetoxypregnenolone | 21-Acetoxypregnenolone is a derivative of Pregnenolone (HY-B0151) with anti-inflammation activity. 21-Acetoxypregnenolone can be used for rheumatoid arthritis research. | |||||||||||||||||||||
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Progesterone (Standard) | 99.20% | Progesterone (Standard) is the analytical standard of Progesterone. This product is intended for research and analytical applications. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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Progesterone-13C5 | Progesterone-13C5 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | |||||||||||||||||||||
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Progesterone-13C3 | 99.60% | Progesterone-13C3 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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Progesterone-13C2 | 99.7% | Progesterone-13C2 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy. | ||||||||||||||||||||
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(S)-1-((8S,9S,10R,13S,14S,17S)-10,13-Dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)ethyl acetate (Progesterone Impurity) (Standard) | ≥98% | |||||||||||||||||||||
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Progesterone impurity 8 | Progesterone impurity 8 (Isoprogesterone) is an impurity of Progesterone. | |||||||||||||||||||||
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References
- [1]. Lother A, et al. Deoxycorticosterone Acetate/Salt-Induced Cardiac But Not Renal Injury Is Mediated By Endothelial Mineralocorticoid Receptors Independently From Blood Pressure. Hypertension. 2016 Jan;67(1):130-8. [Content Brief]
- [2]. Lu NZ, et al. International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors. Pharmacol Rev. 2006 Dec;58(4):782-97. [Content Brief]
