57-15-8
Chemical Structure
Chlorobutanol
- CAS No.: 57-15-8
- Formula:C4H7Cl3O
- Molecular Weight:177.46
IUPAC Name: 1,1,1-trichloro-2-methylpropan-2-ol
InChIKey: OSASVXMJTNOKOY-UHFFFAOYSA-N
SMILES: CC(O)(C)C(Cl)(Cl)Cl
Biological Activity: Chlorobutanol is an orally active and potent inhibitor of platelet aggregation and release and a pharmaceutical preservative with antibacterial activity. Chlorobutanol inhibits thromboxane B2 formation, ATP release, and elevation of cytosolic free calcium caused by collagen, ADP, epinephrine, arachidonic acid and thrombin. Chlorobutanol is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol is widely used in food and cosmetic industry[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Chlorobutanol | 98.0% | Chlorobutanol is an orally active and potent inhibitor of platelet aggregation and release and a pharmaceutical preservative with antibacterial activity. Chlorobutanol inhibits thromboxane B2 formation, ATP release, and elevation of cytosolic free calcium caused by collagen, ADP, epinephrine, arachidonic acid and thrombin. Chlorobutanol is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol is widely used in food and cosmetic industry. | ||||||||||||||||||||
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Chlorobutanol (Standard) | ≥98% | Chlorobutanol (Standard) is the analytical standard of Chlorobutanol. This product is intended for research and analytical applications. Chlorobutanol is a pharmaceutical preservative. Chlorobutanol is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol is widely used in food and cosmetic industry. | ||||||||||||||||||||
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- [1]. Smoak IW, et al. Chlorobutanol: maternal serum levels and placental transfer in the mouse. Vet Hum Toxicol. 1997 Oct;39(5):287-90. [Content Brief]
- [2]. Chen SL, et al. Chlorobutanol, a preservative of desmopressin, inhibits human platelet aggregation and release in vitro. Thromb Haemost. 1990 Nov 30;64(3):473-7. [Content Brief]
- [3]. Fischer M. Effects of chlorobutanol on primary and secondary endings of isolated cat muscle spindles. Brain Res. 2000 Jan 31;854(1-2):106-21. [Content Brief]
- [4]. Jeong D, et al. In Vivo Evaluation of the Oral Toxicity of the Chlorobutanol. Toxics. 2022 Jan 7;10(1):24. [Content Brief]
