5725-91-7
5725-91-7
Chemical Structure
7-Ethoxyresorufin
Synonym(s): Resorufin ethyl ether
- CAS No.: 5725-91-7
- Formula:C14H11NO3
- Molecular Weight:241.24
IUPAC Name: 7-ethoxy-3H-phenoxazin-3-one
InChIKey: CRCWUBLTFGOMDD-UHFFFAOYSA-N
SMILES: O=C1C=CC2=NC3=C(C=C(OCC)C=C3)OC2=C1
Biological Activity: 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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7-Ethoxyresorufin | 99.61% | 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase. | ||||||||||||||||||||
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7-Ethoxyresorufin-d5 | 98.89% | 7-Ethoxyresorufin-d5 is deuterium labeled 7-Ethoxyresorufin. 7-Ethoxyresorufin (Resorufin ethyl ether) is a fluorometric substrate and competitive inhibitor of cytochrome P450, especially CYP1A1. 7-Ethoxyresorufin also inhibits NO synthase. | ||||||||||||||||||||
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References
- [1]. C G Li, et al. Inhibition of NO-medicate responses by 7-ethoxyresorufin, a substrate and competitive inhibitor of cytochrome P450. Br J Pharmacol. 1996 May;118(1):57-62. [Content Brief]
- [2]. Thomas K H Chang, et al. Enzymatic analysis of cDNA-expressed human CYP1A1, CYP1A2, and CYP1B1 with 7-ethoxyresorufin as substrate. Methods Mol Biol. 2006;320:85-90. [Content Brief]
- [3]. Grafstöm R, et al. Inhibitors of 7-ethoxyresorufin and 7-ethoxycoumarin de-ethylases in rat small intestinal microsomes and cells. Drug Chem Toxicol. 1981;4(2):147-59. [Content Brief]
- [4]. Pohl RJ, et al. A rapid method for assaying the metabolism of 7-ethoxyresorufin by microsomal subcellular fractions. Anal Biochem. 1980 Sep 1;107(1):150-5. [Content Brief]
