57756-45-3
57756-45-3
Chemical Structure
WAY 629
- CAS No.: 57756-45-3
- Formula:C15H18N2
- Molecular Weight:226.32
IUPAC Name: 1,2,3,4,8,9,10,11-octahydro-[1,4]diazepino[6,7,1-jk]carbazole
InChIKey: OIGHTPDWPMLMGT-UHFFFAOYSA-N
SMILES: N1(CCNC2)C3=C(C4=CC=CC2=C41)CCCC3
Biological Activity: WAY 629 is a potent and selective 5-HT2C agonist with EC50s of 426, 260000 nM for 5-HT2C and 5-HT2A, respectively. WAY 629 decreases feeding behavior[1][2].
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WAY 629 | WAY 629 is a potent and selective 5-HT2C agonist with EC50s of 426, 260000 nM for 5-HT2C and 5-HT2A, respectively. WAY 629 decreases feeding behavior. | |||||||||||||||||||||
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References
- [1]. Sabb AL, et al. Cycloalkyl[b][1,4]benzodiazepinoindoles are agonists at the human 5-HT2C receptor. Bioorg Med Chem Lett. 2004 May 17;14(10):2603-7. [Content Brief]
- [2]. Aoki M, et al. Involvement of serotonin 2C receptor RNA editing in accumbal neuropeptide Y expression and behavioural despair. Eur J Neurosci. 2016 May;43(9):1219-28. [Content Brief]
Keywords
