58-40-2
58-40-2
Chemical Structure
Promazine
Synonym(s): Romtiazin; Ampazine; Berophen
- CAS No.: 58-40-2
- Formula:C17H20N2S
- Molecular Weight:284.42
IUPAC Name: N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
InChIKey: ZGUGWUXLJSTTMA-UHFFFAOYSA-N
SMILES: CN(C)CCCN1C2=C(C=CC=C2)SC3=CC=CC=C13
Biological Activity: Promazine (Romtiazin) is an antipsychotic and a dopamine receptor D2 antagonist. Promazine inhibits dopaminergic neurotransmission[1][2].
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Promazine | Promazine (Romtiazin) is an antipsychotic and a dopamine receptor D2 antagonist. Promazine inhibits dopaminergic neurotransmission. | |||||||||||||||||||||
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References
- [1]. Gareri P, et al. Conventional and atypical antipsychotics in the elderly : a review. Clin Drug Investig. 2003;23(5):287-322. [Content Brief]
- [2]. Myers PR, et al. Characterization of a depolarizing dopamine response in a vertebrate neuronal somatic cell hybrid. J Cell Physiol. 1977;91(1):103-118. [Content Brief]
