58594-72-2
Chemical Structure
Imazalil sulfate
Synonym(s): Enilconazolel sulfate
- CAS No.: 58594-72-2
- Formula:C14H16Cl2N2O5S
- Molecular Weight:395.26
IUPAC Name: 1-(2-(allyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole sulfate
InChIKey: XVTXMTOYQVRHSK-UHFFFAOYSA-N
SMILES: C=CCOC(C1=CC=C(Cl)C=C1Cl)CN2C=CN=C2.O=S(O)(O)=O
Biological Activity: Imazalil (Enilconazole) sulfate is a fungicide. Imazalil sulfate has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil sulfate is commonly used to protect various agricultural crops against fungal attack. Imazalil sulfate induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Imazalil sulfate | 99.63% | Imazalil (Enilconazole) sulfate is a fungicide. Imazalil sulfate has oral activity and strongly activates mPXR but not mCAR in mouse liver. Imazalil sulfate is commonly used to protect various agricultural crops against fungal attack. Imazalil sulfate induces developmental abnormalities, gut microbiota dysbiosis, and hepatic metabolism disorder. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Imazalil-d5 sulfate | Imazalil-d5 (sulfate) is the deuterium labeled Imazalil sulfate. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Hiroyuki Kojima, et al. Inhibitory effects of azole-type fungicides on interleukin-17 gene expression via retinoic acid receptor-related orphan receptors α and γ. Toxicol Appl Pharmacol. 2012 Mar 15;259(3):338-45. [Content Brief]
- [2]. Shohei Yoshimaru, et al. Acceleration of murine hepatocyte proliferation by imazalil through the activation of nuclear receptor PXR. J Toxicol Sci. 2018;43(7):443-450. [Content Brief]
- [3]. Cuiyuan Jin, et al. Chronic exposure of mice to low doses of imazalil induces hepatotoxicity at the physiological, biochemical, and transcriptomic levels. Environ Toxicol. 2018 Jun;33(6):650-658. [Content Brief]
Keywords
