59-47-2
59-47-2
Chemical Structure
Mephenesin
- CAS No.: 59-47-2
- Formula:C10H14O3
- Molecular Weight:182.22
IUPAC Name: 3-(o-tolyloxy)propane-1,2-diol
InChIKey: JWDYCNIAQWPBHD-UHFFFAOYSA-N
SMILES: OCC(O)COC1=CC=CC=C1C
Biological Activity: Mephenesin is an NMDA receptor antagonist. Mephenesin is also a central muscle relaxant with antianxiety, muscle-paralyzing and anticonvulsant effects. Mephenesin acts directly on the skeletal muscle fibres to produce skeletal muscle relaxation. Mephenesin is promising for research of spasticity or painful muscle spasm[1][2][3][4][5].
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Mephenesin | 99.69% | Mephenesin is an NMDA receptor antagonist. Mephenesin is also a central muscle relaxant with antianxiety, muscle-paralyzing and anticonvulsant effects. Mephenesin acts directly on the skeletal muscle fibres to produce skeletal muscle relaxation. Mephenesin is promising for research of spasticity or painful muscle spasm. | ||||||||||||||||||||
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Mephenesin (Standard) | ≥98% | Mephenesin (Standard) is the analytical standard of Mephenesin. This product is intended for research and analytical applications. Mephenesin is an NMDA receptor antagonist and Mephenesin is a central muscle relaxant. | ||||||||||||||||||||
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Mephenesin-d3 | Mephenesin-d3 is deuterium labeled Mephenesin. Mephenesin is an NMDA receptor antagonist. Mephenesin is also a central muscle relaxant with antianxiety, muscle-paralyzing and anticonvulsant effects. Mephenesin acts directly on the skeletal muscle fibres to produce skeletal muscle relaxation. Mephenesin is promising for research of spasticity or painful muscle spasm. | |||||||||||||||||||||
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References
- [1]. Mephenesin: abuse and dependence. Prescrire Int. 2013 May;22(138):127-128. [Content Brief]
- [2]. ?cija P, et al. Conformational flexibility of mephenesin. J Phys Chem B. 2014 May 22;118(20):5357-5364. [Content Brief]
- [3]. Crankshaw DP, et al. Mephenesin, methocarbamol, chlordiazepoxide and diazepam: actions on spinal reflexes and ventral root potentials. Br J Pharmacol. 1970 Jan;38(1):148-56. [Content Brief]
- [4]. Ludwig B J, et al. Muscle-paralyzing compounds related to mephenesin[J]. Journal of the American Chemical Society, 1952, 74(8): 1935-1939.
- [5]. DIAZ-RIVERA RS, et al. Muscular relaxation in tetanus with special reference to the effect of mephenesin. Ann Intern Med. 1954 Mar;40(3):563-80. [Content Brief]
