59017-64-0
Chemical Structure
Ioxaglic acid
Synonym(s): P-286
- CAS No.: 59017-64-0
- Formula:C24H21I6N5O8
- Molecular Weight:1268.88
IUPAC Name: 3-((2-hydroxyethyl)carbamoyl)-2,4,6-triiodo-5-(2-(2,4,6-triiodo-3-(N-methylacetamido)-5-(methylcarbamoyl)benzamido)acetamido)benzoic acid
InChIKey: TYYBFXNZMFNZJT-UHFFFAOYSA-N
SMILES: IC(C(C(NCCO)=O)=C(I)C(C(O)=O)=C1I)=C1NC(CNC(C2=C(C(N(C)C(C)=O)=C(I)C(C(NC)=O)=C2I)I)=O)=O
Biological Activity: Ioxaglic acid (P-286) is negatively charged contrast agent, is useful as an inverse indicator for glycosaminoglycan (GAG) used in computed tomography (CT). Ioxaglic acid can be used for imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content[1][2].
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Ioxaglic acid | Ioxaglic acid (P-286) is negatively charged contrast agent, is useful as an inverse indicator for glycosaminoglycan (GAG) used in computed tomography (CT). Ioxaglic acid can be used for imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content. | |||||||||||||||||||||
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- [1]. Gonsette RE, et, al. New contrast media in cerebral angiography: animal experiments and preliminary clinical studies. Invest Radiol. Nov-Dec 1980;15(6 Suppl):S270-4. [Content Brief]
- [2]. Baer K, et, al. Spectral CT imaging of human osteoarthritic cartilage via quantitative assessment of glycosaminoglycan content using multiple contrast agents. APL Bioeng. 2021 Apr 1;5(2):026101. [Content Brief]
Keywords
