60008-03-9
60008-03-9
Chemical Structure
Glabrene
- CAS. Nr.: 60008-03-9
- Formula:C20H18O4
- Molecular Weight:322.35
IUPAC Name: 2',2'-dimethyl-2H,2'H-[3,8'-bichromene]-5',7-diol
InChIKey: NGGYSPUAKQMTNP-UHFFFAOYSA-N
SMILES: OC1=C2C=CC(C)(C)OC2=C(C3=CC4=CC=C(O)C=C4OC3)C=C1
Biological Activity: Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC50 of 3.5 μM[1][2].
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Glabrene | Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is a tyrosinase inhibitor with an IC50 of 3.5 μM. | |||||||||||||||||||||
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References
- [1]. Somjen D, et al. Estrogenic activity of glabridin and glabrene from licorice roots on human osteoblasts and prepubertal rat skeletal tissues. J Steroid Biochem Mol Biol. 2004 Aug;91(4-5):241-6. [Content Brief]
- [2]. Nerya O, et al. Glabrene and isoliquiritigenin as tyrosinase inhibitors from licorice roots. J Agric Food Chem. 2003 Feb 26;51(5):1201-7 [Content Brief]
