601-53-6
Chemical Structure
Coprostanone
Synonym(s): 5β-Cholestan-3-one
- CAS No.: 601-53-6
- Formula:C27H46O
- Molecular Weight:386.65
IUPAC Name: (5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-((R)-6-methylheptan-2-yl)hexadecahydro-3H-cyclopenta[a]phenanthren-3-one
InChIKey: PESKGJQREUXSRR-JDIFZLMISA-N
SMILES: C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCCC(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4([C@](CC(CC4)=O)([H])CC3)C
Biological Activity: Coprostanone (5β-cholestan-3-one) is an oxysterol and active metabolite of Cholesterol (HY-N0322). Coprostanone induces apoptosis in primary dog gallbladder epithelial cells. Coprostanone is promising for research of colon cancers or adenomatous polyps[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Coprostanone | 98.25% | Coprostanone (5β-cholestan-3-one) is an oxysterol and active metabolite of Cholesterol (HY-N0322). Coprostanone induces apoptosis in primary dog gallbladder epithelial cells. Coprostanone is promising for research of colon cancers or adenomatous polyps. | ||||||||||||||||||||
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References
- [1]. Seo DW, et al. Oxysterols from human bile induce apoptosis of canine gallbladder epithelial cells in monolayer culture. Am J Physiol Gastrointest Liver Physiol. 2004 Dec;287(6):G1247-56. [Content Brief]
- [2]. Reddy BS, et al. Metabolic epidemiology of colon cancer. Fecal bile acids and neutral sterols in colon cancer patients and patients with adenomatous polyps. Cancer. 1977 Jun;39(6):2533-9. [Content Brief]
