6018-19-5
6018-19-5
Chemical Structure
Sodium 4-aminosalicylate dihydrate
Synonym(s): 4-Aminosalicylic acid sodium salt dihydrate
- CAS No.: 6018-19-5
- Formula:C7H10NNaO5
- Molecular Weight:211.15
IUPAC Name: sodium 4-amino-2-hydroxybenzoate dihydrate
InChIKey: GMUQJDAYXZXBOT-UHFFFAOYSA-M
SMILES: O=C(O[Na])C1=C(O)C=C(N)C=C1.O.O
Biological Activity: Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active[1][1][3].
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Sodium 4-aminosalicylate dihydrate | 99.95% | Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active. | ||||||||||||||||||||
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Sodium 4-aminosalicylate dihydrate (Standard) | ≥98% | Sodium 4-aminosalicylate (dihydrate) (Standard) is the analytical standard of Sodium 4-aminosalicylate (dihydrate). This product is intended for research and analytical applications. Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active. | ||||||||||||||||||||
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References
- [1]. Zheng J, et al. para-Aminosalicylic acid is a prodrug targeting dihydrofolate reductase in Mycobacterium tuberculosis. J Biol Chem. 2013 Aug 9;288(32):23447-56. [Content Brief]
- [3]. Dhaneshwar SS. Colon-specific prodrugs of 4-aminosalicylic acid for inflammatory bowel disease. World J Gastroenterol. 2014 Apr 7;20(13):3564-71. [Content Brief]
