610-92-4
Chemical Structure
2,5-Dihydroxyterephthalic acid
- CAS No.: 610-92-4
- Formula:C8H6O6
- Molecular Weight:198.13
IUPAC Name: 2,5-dihydroxyterephthalic acid
InChIKey: OYFRNYNHAZOYNF-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC(O)=C(C=C1O)C(=O)O
Biological Activity: 2,5-Dihydroxyterephthalic acid is a carboxylic acid ligand with antioxidant properties, which serves as a building block for Zn2+-based metal-organic frameworks (MOFs). 2,5-Dihydroxyterephthalic acid forms stable coordination bonds with transition metal ions, inhibits metal center-water coordination to prevent MOF fluorescence quenching, and enhances the hydrophilicity of MOFs. 2,5-Dihydroxyterephthalic acid acts as a pharmaceutical intermediate to synthesize 2,5-dihydroxyterephthalamide derivatives. 2,5-Dihydroxyterephthalic acid is applicable to relevant research in fields such as organic synthesis[1][2].
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2,5-Dihydroxyterephthalic acid | 2,5-Dihydroxyterephthalic acid is a carboxylic acid ligand with antioxidant properties, which serves as a building block for Zn2+-based metal-organic frameworks (MOFs). 2,5-Dihydroxyterephthalic acid forms stable coordination bonds with transition metal ions, inhibits metal center-water coordination to prevent MOF fluorescence quenching, and enhances the hydrophilicity of MOFs. 2,5-Dihydroxyterephthalic acid acts as a pharmaceutical intermediate to synthesize 2,5-dihydroxyterephthalamide derivatives. 2,5-Dihydroxyterephthalic acid is applicable to relevant research in fields such as organic synthesis. | |||||||||||||||||||||
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References
- [1]. Wang J, et al. Zn(ii)-based metal-organic frameworks with tailored architectures: optimizing fluorescence performance for cell imaging and cancer therapy. RSC advances. 2026 May 13;16(28):25892-25901. [Content Brief]
- [2]. Song Q, et al. Discovery of novel 2,5-dihydroxyterephthalamide derivatives as multifunctional agents for the treatment of Alzheimer's disease. Bioorganic & medicinal chemistry. 2018 Dec 15;26(23-24):6115-6127. [Content Brief]
