6281-58-9
6281-58-9
Chemical Structure
Hydroxychloroquine Impurity F
- CAS No.: 6281-58-9
- Formula:C14H15ClN2
- Molecular Weight:246.74
IUPAC Name: 7-chloro-4-(2-methylpyrrolidin-1-yl)quinoline
InChIKey: GYORBDCAYLXAIL-UHFFFAOYSA-N
SMILES: CC1N(C2=CC=NC3=CC(Cl)=CC=C23)CCC1
Biological Activity: Hydroxychloroquine Impurity F is the impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro[1][2][3].
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Hydroxychloroquine Impurity F | Hydroxychloroquine Impurity F is the impurity of Hydroxychloroquine. Hydroxychloroquine is a synthetic antimalarial agent which can also inhibit Toll-like receptor 7/9 (TLR7/9) signaling. Hydroxychloroquine is efficiently inhibits SARS-CoV-2 infection in vitro. | |||||||||||||||||||||
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References
- [1]. Manzo C, et al. Psychomotor Agitation Following Treatment with Hydroxychloroquine. Drug Saf Case Rep. 2017 Dec;4(1):6. [Content Brief]
- [2]. Lamphier M, et al. Novel small molecule inhibitors of TLR7 and TLR9: mechanism of action and efficacy in vivo. Mol Pharmacol. 2014 Mar;85(3):429-40. [Content Brief]
- [3]. Yao X, et al. In Vitro Antiviral Activity and Projection of Optimized Dosing Design of Hydroxychloroquine for the Treatment of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020 Mar 9. pii: ciaa237. [Content Brief]
Keywords
