628690-75-5
628690-75-5
Chemical Structure
TP003
- CAS No.: 628690-75-5
- Formula:C23H16F3N3O
- Molecular Weight:407.39
IUPAC Name: 2',4-difluoro-5'-(8-fluoro-7-(2-hydroxypropan-2-yl)imidazo[1,2-a]pyridin-3-yl)-[1,1'-biphenyl]-2-carbonitrile
InChIKey: SJMMDWXJSSJHOQ-UHFFFAOYSA-N
SMILES: N#CC1=CC(F)=CC=C1C2=CC(C3=CN=C4C(F)=C(C(C)(O)C)C=CN43)=CC=C2F
Biological Activity: TP003 is a non-selective benzodiazepine site agonist with EC50s of 20.3, 10.6, 3.24, 5.64 nM for α1β2γ2, α2β3γ2, α3β3γ2, α5β2γ2, respectively. TP003 induces anxiolysis via α2GABAA receptors[1].
| Cat. No. | Nom du produit | Pureté | Description | Pricing | |||||||||||||||||||
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TP003 | 98.09% | TP003 is a non-selective benzodiazepine site agonist with EC50s of 20.3, 10.6, 3.24, 5.64 nM for α1β2γ2, α2β3γ2, α3β3γ2, α5β2γ2, respectively. TP003 induces anxiolysis via α2GABAA receptors. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.67
HY-153584MRK-898 -
Similarity Score 0.57
HY-19505TPA-023B -
Similarity Score 0.57
HY-123840MRK-623 -
Similarity Score 0.48
HY-W1135843ARN-75039 -
Similarity Score 0.48
HY-171293Protein kinase inhibitor 15 -
Similarity Score 0.48
HY-11048NS11394 -
Similarity Score 0.47
HY-149916A2AR-antagonist-1 -
Similarity Score 0.47
HY-171291Protein kinase inhibitor 14 -
Similarity Score 0.47
HY-183528Anticoccidial agent-1 -
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