63758-79-2
63758-79-2
Chemical Structure
Indalpine
Synonym(s): LM 5008
- CAS No.: 63758-79-2
- Formula:C15H20N2
- Molecular Weight:228.33
IUPAC Name: 3-(2-(piperidin-4-yl)ethyl)-1H-indole
InChIKey: SADQVAVFGNTEOD-UHFFFAOYSA-N
SMILES: C1(CCC2CCNCC2)=CNC3=C1C=CC=C3
Biological Activity: Indalpine (LM 5008) is a potent and selective 5-HT uptake blocker. Indalpine is potent in displacing 3H-5-HT bound to brain membranes with the IC50 of 36 μM[1]. Indalpine, two antidepressant agent[2].
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Indalpine | Indalpine (LM 5008) is a potent and selective 5-HT uptake blocker. Indalpine is potent in displacing 3H-5-HT bound to brain membranes with the IC50 of 36 μM. Indalpine, two antidepressant agent. | |||||||||||||||||||||
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References
- [1]. R Samanin, et al. Further studies on the mechanism of serotonin-dependent anorexia in rats. Psychopharmacology (Berl). 1980;68(1):99-104. [Content Brief]
- [2]. P Blier, et al. Effects of the two antidepressant drugs mianserin and Indalpine on the serotonergic system: single-cell studies in the rat. Psychopharmacology (Berl). 1984;84(2):242-9. [Content Brief]
