638-32-4
638-32-4
Chemical Structure
Succinamic acid
- CAS No.: 638-32-4
- Formula:C4H7NO3
- Molecular Weight:117.10
IUPAC Name: 4-amino-4-oxobutanoic acid
InChIKey: JDVPQXZIJDEHAN-UHFFFAOYSA-N
SMILES: O=C(O)CCC(N)=O
Biological Activity: Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC50 of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336)[1][2].
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Succinamic acid | Succinamic acid is a weak inhibitor for human LL-xylose reductase with an IC50 of 1.45 mM. Succinamic acid can be used as a linker for synthesis of CQ-16 (HY-169336). | |||||||||||||||||||||
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References
- [1]. Carbone V, et al., Structure-based discovery of human L-xylulose reductase inhibitors from database screening and molecular docking. Bioorg Med Chem. 2005 Jan 17;13(2):301-12. [Content Brief]
- [2]. Chen Q, et al., A Prostate-Specific Membrane Antigen-Targeting Small Molecule-Drug Conjugate Strategy to Overcome the Hematological Toxicity of Olaparib. J Med Chem. 2024 Nov 14;67(21):19586-19611. [Content Brief]
