6386-58-9
Chemical Structure
Probucol dithiobisphenol
Synonym(s): DTBP
- CAS No.: 6386-58-9
- Formula:C28H42O2S2
- Molecular Weight:474.76
IUPAC Name: 4,4'-disulfanediylbis(2,6-di-tert-butylphenol)
InChIKey: NEUPRVAMTYHIQV-UHFFFAOYSA-N
SMILES: CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)SSC2=CC(=C(C(=C2)C(C)(C)C)O)C(C)(C)C
Biological Activity: Probucol dithiobisphenol (DTBP) is the derivative of Probucol (HY-B0388). Probucol dithiobisphenol induces the production of heme oxygenase 1 (HO-1), and exhibits antioxidant activity. Probucol dithiobisphenol inhibits atherosclerotic lesions in Apoe−/− mice aorta, promotes re-endothelialization of aorta and inhibits restenosis in rabbit arterial injury models. Probucol dithiobisphenol is orally active[1].
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Probucol dithiobisphenol | Probucol dithiobisphenol (DTBP) is the derivative of Probucol (HY-B0388). Probucol dithiobisphenol induces the production of heme oxygenase 1 (HO-1), and exhibits antioxidant activity. Probucol dithiobisphenol inhibits atherosclerotic lesions in Apoe−/− mice aorta, promotes re-endothelialization of aorta and inhibits restenosis in rabbit arterial injury models. Probucol dithiobisphenol is orally active. | |||||||||||||||||||||
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Keywords
