642-83-1
Chemical Structure
Aceglatone
- No. CAS: 642-83-1
- Formula:C10H10O8
- Molecular Weight:258.18
IUPAC Name: (3R,3aS,6S,6aS)-2,5-dioxohexahydrofuro[3,2-b]furan-3,6-diyl diacetate
InChIKey: ZOZKYEHVNDEUCO-DKXJUACHSA-N
SMILES: CC(O[C@H]1[C@]2([H])[C@@](OC1=O)([H])[C@H](C(O2)=O)OC(C)=O)=O
Biological Activity: Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells[1].
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Aceglatone | Aceglatone, an antineoplastic agent, is a β-glucuronidase inhibitor. Aceglatone is a compound that inhibits colon carcinogenesis and prevents the induction of colon cancer by inhibiting the hydrolysis of glucuronides. Aceglatone reduces cell proliferation, induces apoptosis and inhibits DNA synthesis in human colon cancer cells. | |||||||||||||||||||||
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Keywords
