642072-48-8
642072-48-8
Chemical Structure
MEL24
- CAS No.: 642072-48-8
- Formula:C17H18N4O3
- Molecular Weight:326.35
IUPAC Name: 1,3-dimethyl-5-(2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)pyrimidine-2,4,6(1H,3H,5H)-trione
InChIKey: FOUOSAVQDWJOGI-UHFFFAOYSA-N
SMILES: O=C1N(C)C(C(C2NCCC3=C2NC4=C3C=CC=C4)C(N1C)=O)=O
Biological Activity: MEL24 is an Mdm2 E3 ligase inhibitor that reduces cell survival and increases sensitivity to DNA damaging agents in a p53-dependent manner for in vitro antitumor studies[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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MEL24 | 98.0% | MEL24 is an Mdm2 E3 ligase inhibitor that reduces cell survival and increases sensitivity to DNA damaging agents in a p53-dependent manner for in vitro antitumor studies. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.76
HY-148106MEL23 -
Similarity Score 0.56
HY-N18435Komaroidine -
Similarity Score 0.56
HY-331691,2,3,4-Tetrahydro-β-carboline-1-carboxylic acid -
Similarity Score 0.53
HY-N7569Demethoxyfumitremorgin C -
Similarity Score 0.52
HY-184083Fenharmane -
Similarity Score 0.52
HY-W250061(-)-(1S,3S)-MTCA -
Similarity Score 0.50
HY-N11479Vallesiachotamine -
Similarity Score 0.50
HY-106115Vintoperol -
Similarity Score 0.50
HY-121936AYohimbic acid hydrate -
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