Yohimbic acid hydrate

Cat. No.: HY-121936A Purity: 99.96%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Yohimbic acid hydrate is an amphoteric demethylated derivative of Yohimbine (HY-12715). Yohimbic acid hydrate exhibits vasodilatory action. Yohimbic acid hydrate also can be used for the research of osteoarthritis (OA).

For research use only. We do not sell to patients.

Yohimbic acid hydrate Chemical Structure

CAS No. : 207801-27-2

Size	Price	Stock	Quantity
5 mg	USD 290	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 460	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Yohimbic acid hydrate:

Yohimbic acid In-stock

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Purity & Documentation
References
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Description

Molecular Weight

358.43

Formula

C₂₀H₂₆N₂O₄

CAS No.

207801-27-2

Appearance

Solid

Color

White to off-white

SMILES

[H][C@]12C3=C(CCN1C[C@]4([H])CC[C@@H]([C@@H]([C@@]4([H])C2)C(O)=O)O)C(C=CC=C5)=C5N3.O

Structure Classification

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

DMSO : ≥ 125 mg/mL (348.74 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.7899 mL	13.9497 mL	27.8995 mL
5 mM	0.5580 mL	2.7899 mL	5.5799 mL
10 mM	0.2790 mL	1.3950 mL	2.7899 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.96%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (254 KB) HNMR (289 KB) LCMS (264 KB)

Handling Instructions (2659 KB)

References

[1]. HAMET R. Demonstration of the direct vasodilatory action of yohimbic acid and Py-tetrahydroquinoline. C R Hebd Seances Acad Sci. 1960 Jun 27;250:4473-5. [Content Brief]

[2]. HAMET R. Sympatholytic activity and toxicity of an amphoteric demethylated derivative of yohimbine: yohimbic acid. C R Hebd Seances Acad Sci. 1951 Oct 29;233(18):1069-71. [Content Brief]

[3]. Wang S, et, al. Significantly dysregulated genes in osteoarthritic labrum cells identified through gene expression profiling. Mol Med Rep. 2019 Aug; 20(2): 1716-1724. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.7899 mL	13.9497 mL	27.8995 mL	69.7486 mL
	5 mM	0.5580 mL	2.7899 mL	5.5799 mL	13.9497 mL
	10 mM	0.2790 mL	1.3950 mL	2.7899 mL	6.9749 mL
	15 mM	0.1860 mL	0.9300 mL	1.8600 mL	4.6499 mL
	20 mM	0.1395 mL	0.6975 mL	1.3950 mL	3.4874 mL
	25 mM	0.1116 mL	0.5580 mL	1.1160 mL	2.7899 mL
	30 mM	0.0930 mL	0.4650 mL	0.9300 mL	2.3250 mL
	40 mM	0.0697 mL	0.3487 mL	0.6975 mL	1.7437 mL
	50 mM	0.0558 mL	0.2790 mL	0.5580 mL	1.3950 mL
	60 mM	0.0465 mL	0.2325 mL	0.4650 mL	1.1625 mL
	80 mM	0.0349 mL	0.1744 mL	0.3487 mL	0.8719 mL
	100 mM	0.0279 mL	0.1395 mL	0.2790 mL	0.6975 mL

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Yohimbic acid207801-27-2OthersamphotericdemethylatedderivativeYohimbinevasodilatoryactionosteoarthritisOAInhibitorinhibitorinhibit

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Yohimbic acid hydrate

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Other Forms of Yohimbic acid hydrate: