66529-17-7
66529-17-7
Chemical Structure
Midaglizole
Synonym(s): (±)-DG5128 free base; DG5128 free base
- CAS No.: 66529-17-7
- Formula:C16H17N3
- Molecular Weight:251.33
IUPAC Name: 2-(2-(4,5-dihydro-1H-imidazol-2-yl)-1-phenylethyl)pyridine
InChIKey: TYZQFNOLWJGHRZ-UHFFFAOYSA-N
SMILES: C1(C(C2=CC=CC=C2)CC3=NCCN3)=NC=CC=C1
Biological Activity: Midaglizole ((±)-DG5128 free base, DG5128 free base) is a potent α2-adrenoceptor antagonist. Midaglizole is a hypoglycemic agent. Midaglizole increases blood pressure and reduces blood glucose levels in vivo[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Midaglizole | 98.28% | Midaglizole ((±)-DG5128 free base, DG5128 free base) is a potent α2-adrenoceptor antagonist. Midaglizole is a hypoglycemic agent. Midaglizole increases blood pressure and reduces blood glucose levels in vivo. | ||||||||||||||||||||
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Midaglizole (Standard) | ≥98% | Midaglizole (Standard) is the analytical standard of Midaglizole. This product is intended for research and analytical applications. Midaglizole ((±)-DG5128 free base; DG5128 free base) is a potent α2-adrenoceptor antagonist. Midaglizole is a hypoglycemic agent. Midaglizole increases blood pressure and reduces blood glucose levels in vivo. | ||||||||||||||||||||
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References
- [1]. Hirohashi M, et al. Intrinsic pressor activity of midaglizole, an alpha-2 adrenoceptor antagonist, in pithed rats. Jpn J Pharmacol. 1990 Aug;53(4):519-20. [Content Brief]
- [2]. Ohneda K, et al. Mechanism of insulin secretion by midaglizole. Diabetes Res Clin Pract. 1993 Feb;19(2):127-32. [Content Brief]
- [3]. Proks P, et al. Inhibition of recombinant K(ATP) channels by the antidiabetic agents midaglizole, LY397364 and LY389382. Eur J Pharmacol. 2002 Sep 27;452(1):11-9. [Content Brief]
