67727-97-3
Chemical Structure
α-MSH (11-13)
Synonym(s): ACTH-(11-13); Lys-Pro-Val; H-Lys-Pro-Val-OH
- CAS No.: 67727-97-3
- Formula:C16H30N4O4
- Molecular Weight:342.43
IUPAC Name: L-lysyl-L-prolyl-L-valine
InChIKey: YSPZCHGIWAQVKQ-AVGNSLFASA-N
SMILES: O=C(N1[C@@H](CCC1)C(N[C@@H](C(C)C)C(O)=O)=O)[C@H](CCCCN)N
Biological Activity: α-MSH (11-13) (ACTH-(11-13)) is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) can be used in research related to traumatic brain injury, fever, and bacterial infections[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
α-MSH (11-13) | α-MSH (11-13) (ACTH-(11-13)) is a C-terminal tripeptide of α-MSH that can cross the blood-brain barrier. α-MSH (11-13) exhibits antipyretic, anti-inflammatory, and antibacterial activities. α-MSH (11-13) also exerts neuroprotective effects after traumatic brain injury by inhibiting excessive activation of microglia and reducing neuronal apoptosis. α-MSH (11-13) can be used in research related to traumatic brain injury, fever, and bacterial infections. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
- [1]. Schaible EV, et al. Single administration of tripeptide α-MSH(11-13) attenuates brain damage by reduced inflammation and apoptosis after experimental traumatic brain injury in mice. PLoS One. 2013;8(8):e71056. Published 2013 Aug 5. [Content Brief]
- [2]. Richards DB, et al. Effect of alpha-MSH 11-13 (lysine-proline-valine) on fever in the rabbit. Peptides. 1984;5(4):815-817. [Content Brief]
- [3]. Cutuli M, et al. Antimicrobial effects of alpha-MSH peptides. J Leukoc Biol. 2000 Feb;67(2):233-9. [Content Brief]
Keywords
