67879-58-7
Chemical Structure
Caftaric acid
Synonym(s): trans-Caftaric acid
- CAS No.: 67879-58-7
- Formula:C13H12O9
- Molecular Weight:312.23
IUPAC Name: (2R,3R)-2-(((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)-3-hydroxysuccinic acid
InChIKey: SWGKAHCIOQPKFW-JTNORFRNSA-N
SMILES: O=C(O)[C@H](OC(/C=C/C1=CC=C(O)C(O)=C1)=O)[C@@H](O)C(O)=O
Biological Activity: Caftaric acid (trans-Caftaric acid) is a polyphenolic antidiuretic, antioxidant and anti-apoptotic agent that can be hydrolyzed by intestinal microbial esterases. Caftaric acid exerts its antioxidant and potential anti-inflammatory effects mainly through intestinal microbial metabolism. Caftaric acid can reduce renal damage, restore electrolyte balance, renal function indicators and antioxidant enzyme activities in a rat albinism model, and further exert anti-oxidative stress and anti-inflammatory activities[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Caftaric acid | 99.96% | Caftaric acid (trans-Caftaric acid) is a polyphenolic antidiuretic, antioxidant and anti-apoptotic agent that can be hydrolyzed by intestinal microbial esterases. Caftaric acid exerts its antioxidant and potential anti-inflammatory effects mainly through intestinal microbial metabolism. Caftaric acid can reduce renal damage, restore electrolyte balance, renal function indicators and antioxidant enzyme activities in a rat albinism model, and further exert anti-oxidative stress and anti-inflammatory activities. | ||||||||||||||||||||
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Caftaric acid (Standard) | ≥98% | Caftaric acid (Standard) is the analytical standard of Caftaric acid. This product is intended for research and analytical applications. Caftaric acid is a natural compound. | ||||||||||||||||||||
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- [1]. Gonthier MP, et al. Microbial metabolism of caffeic acid and its esters chlorogenic and caftaric acids by human faecal microbiota in vitro. Biomed Pharmacother. 2006 Nov;60(9):536-40. [Content Brief]
- [2]. Koriem KMM, Arbid MS. Role of caftaric acid in lead-associated nephrotoxicity in rats via antidiuretic, antioxidant and anti-apoptotic activities. J Complement Integr Med. 2017 Nov 17;15(2):/j/jcim.2018.15.issue-2/jcim-2017-0024/jcim-2017-0024.xml. [Content Brief]
- [3]. Ekinci Akdemir FN, Güler MC, Eraslan E, Tanyeli A, Yildirim S. Caftaric acid attenuates kidney and remote organ damage induced by renal ischemia-reperfusion injury. Sci Rep. 2024 Dec 28;14(1):31385. [Content Brief]
