683-57-8
683-57-8
Chemical Structure
2-Bromoacetamide
- CAS No.: 683-57-8
- Formula:C2H4BrNO
- Molecular Weight:137.96
IUPAC Name: 2-bromoacetamide
InChIKey: JUIKUQOUMZUFQT-UHFFFAOYSA-N
SMILES: O=C(N)CBr
Biological Activity: 2-Bromoacetamide is a disinfection byproduct. 2-Bromoacetamide can inactivate liver alcohol dehydrogenase and interfere with microtubule and actin cytoskeletal function. 2-Bromoacetamide is a potent developmental toxicant in animals[1][2][3].
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2-Bromoacetamide | 99.77% | 2-Bromoacetamide is a disinfection byproduct. 2-Bromoacetamide can inactivate liver alcohol dehydrogenase and interfere with microtubule and actin cytoskeletal function. 2-Bromoacetamide is a potent developmental toxicant in animals. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.79
HY-34477R2-Iodoacetamide (Standard) -
Similarity Score 0.79
HY-W0106292-Chloroacetamide -
Similarity Score 0.78
HY-W015972Propionamide -
Similarity Score 0.76
HY-Y11232-Aminoacetamide hydrochloride -
Similarity Score 0.74
HY-W088319Butyramide -
Similarity Score 0.71
HY-1336652,2-Dibromoacetamide -
Similarity Score 0.71
HY-133842RAcetoacetamide (Standard) -
Similarity Score 0.71
HY-W010596SMalonamide-13C3 -
Explore the MedChemAI to find more analogs
References
- [1]. Fries RW, et al. Activation of liver alcohol dehydrogenases by imidoesters generated in solution. Biochemistry. 1975;14(23):5233‐5238. [Content Brief]
- [2]. Zhang C, et al. Developmental toxicity of 2-bromoacetamide on peri- and early post-implantation mouse embryos in vitro. Ecotoxicol Environ Saf. 2023 Mar 1;252:114612. [Content Brief]
- [3]. Zhang C, et al. 2-bromoacetamide exposure impairs oocyte maturation in mice and humans primarily via disrupting the cytoskeleton. Ecotoxicol Environ Saf. 2024 Mar 1;272:116105. [Content Brief]
