702676-93-5
702676-93-5
Chemical Structure
BX-320
- CAS No.: 702676-93-5
- Formula:C23H31BrN8O3
- Molecular Weight:547.45
IUPAC Name: N1-(3-((5-bromo-2-((3-(pyrrolidine-1-carboxamido)phenyl)amino)pyrimidin-4-yl)amino)propyl)-2,2-dimethylmalonamide
InChIKey: ZNSULAZTNWFKEW-UHFFFAOYSA-N
SMILES: O=C(C(C)(C)C(N)=O)NCCCNC1=C(Br)C=NC(NC2=CC=CC(NC(N3CCCC3)=O)=C2)=N1
Biological Activity: BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect[1].
| Cat. No. | 상품명 | Purity | 제품 설명 | Pricing | |||||||||||||||||||
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BX-320 | 99.4% | BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect. | ||||||||||||||||||||
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References
Keywords
