702676-93-5
702676-93-5
Chemical Structure
BX-320
- CAS No.: 702676-93-5
- Formula:C23H31BrN8O3
- Molecular Weight:547.45
IUPAC Name: N1-(3-((5-bromo-2-((3-(pyrrolidine-1-carboxamido)phenyl)amino)pyrimidin-4-yl)amino)propyl)-2,2-dimethylmalonamide
InChIKey: ZNSULAZTNWFKEW-UHFFFAOYSA-N
SMILES: O=C(C(C)(C)C(N)=O)NCCCNC1=C(Br)C=NC(NC2=CC=CC(NC(N3CCCC3)=O)=C2)=N1
Biological Activity: BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BX-320 | 99.4% | BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-11005BX-912 -
Similarity Score 0.67
HY-10514BX795 -
Similarity Score 0.57
HY-183099TBK1 ligand 3 -
Similarity Score 0.56
HY-176334TBK1 ligand 2 -
Similarity Score 0.54
HY-18315Bayer-18 -
Similarity Score 0.51
HY-13018AMRT67307 hydrochloride -
Similarity Score 0.51
HY-13018BMRT67307 dihydrochloride -
Similarity Score 0.51
HY-13018MRT67307 -
Similarity Score 0.51
HY-176335TBK1 ligand 2-C-O-C4-O-C3-O-C-amide -
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