country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-183099

Copy Link Print Information

TBK1 ligand 3

TBK1 ligand 3 is a TBK1 ligand, which can be used as a target protein ligand for the synthesis of PROTAC UNC8209 (HY-183098) and UNC8461 (HY-183100).

For research use only. We do not sell to patients.

CAS No.: 2115897-10-2
Formula: C₁₉H₂₄BrN₅O₂
Molecular Weight:434.33

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TBK1 ligand 3 Chemical Structure

CAS No.: 2115897-10-2

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

TBK1 ligand 3 is a TBK1 ligand, which can be used as a target protein ligand for the synthesis of PROTAC UNC8209 (HY-183098) and UNC8461 (HY-183100)^[1].

IC₅₀ & Target

TBK1

All IKK Isoforms :

Chemical Information

CAS No. 2115897-10-2
Molecular Weight 434.33
Formula C₁₉H₂₄BrN₅O₂
SMILES

CN(C(C1CCC1)=O)CCCNC2=NC(NC3=CC=C(O)C=C3)=NC=C2Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Liao C, et al. Selective degradation of TBK1 uncovers mechanistic insights into blocking ccRCC progression. Cell Chem Biol. 2026 Apr 16;33(4):461-473.e7. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

Get Quote In-stock

Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

TBK1 ligand 3

All IKK Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

TBK1 ligand 3 Related Classifications

HY-183099 Related Classifications